Position: Research Associate (postdoctoral)
Institution: The University of Texas at Dallas
Location: Richardson, TX
Deadline: December 1, 2001 or when position is filled
Start date: January 1, 2002
Project Description: The Human Genome Project and modern molecular biology
techniques have produced an abundance of data on the genes and gene
products, in particular proteins, that control cell function. On average,
proteins interact with five other proteins to form the complex signaling and
regulatory networks that integrate the input signals to a cell and
orchestrate its response. Pharmaceutical companies are very interested in
understanding how malfunctioning regulatory networks can lead to disease;
indeed, of the 500 different molecular targets at which current drug
therapies are aimed, about half are cell surface receptors, the starting
point of signaling networks. Unlocking the therapeutic potential of the
remaining, downstream components of signaling networks will require more
knowledge of protein-protein interactions, but will also need mathematical
and computational tools for integrating these isolated pieces of data into a
single system, whose overall response can then be studied. The goal of this
project is to develop mathematical techniques and tools for modeling and
analyzing receptor-mediated signaling networks. The project is a part of a
multidiscliplinary effort that involves collaboration with a major
pharmaceutical company. The postdoctoral fellow will have the opportunity to
interact with both experimental and theoretical scientists in both the
academic and industrial environment. The position starts January 1, 2002
and lasts for two years. Review of applications will begin December 1,
2001.
Qualifications: Candidate should have a Ph.D. or M.D. with experience in
mathematical and computational modeling of biological systems.
Application: Send curriculum vitae, the names of three references, and a
description of past research experience and research interests to the
following address:
M. Saleet Jafri
Department of Mathematical Sciences EC35
The University of Texas at Dallas
Box 830688
Richardson, TX 75083
Phone: 972-883-4436
Fax: 972-883-6622
email: jafri@utdallas.edu
UT-Dallas is an EEO/AA employer
M. Saleet Jafri
Assistant Professor
Department of Mathematical Sciences
The University of Texas at Dallas
Box 830688, EC35
Richardson, TX 75081
(972)-883-4436 (phone)
(972)-883-6622 (fax)
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