New York Academy of Sciences Conference

Kathleen Schrader (kschrader@nyas.org)
Thu, 4 Dec 1997 11:49:45 -0500

"Neuronal Mechanisms for Generating Locomotor Activity"

March 20 - 23, 1998
The Rockefeller University -- New York City

A New York Academy of Sciences Conference

Registration Information

New York Academy of Sciences
2 East 63rd Street
New York, NY 10021
http://www.nyas.org
Serving Science,Technology, and Society Worldwide Since 1817

Our understanding of the neuronal basis of locomotion in higher
vertebrates has progressed considerably in the past few years. Among
the most important developments is a number of in vitro spinal cord
preparations which enable researchers to study locomotor pattern
generation from cellular and molecular perspectives. Some of these
findings are beginning to be used in clinical applications on
individuals with spinal cord damage.

The latest developments in the neuronal basis for locomotion will be
reviewed at this conference. The conference will begin with an overview
of the best understood vertebrate and invertebrate models. Other
sessions will focus on spinal locomotor networks in higher vertebrates,
neurotransmitter control of pattern generating networks, sensory inputs
to central pattern generators, modeling of well understood networks, and
molecular biological approaches to understanding neural network function
and modulation. Sessions will also be held on developmental and
comparative studies of locomotor pattern generation, and on clinical
applications of spinal locomotor network analysis in animals and man. A
final panel discussion will synthesize the general principles for
rhythmic pattern generation and will discuss avenues for future
research.

This conference will be of interest to researchers in neuroscience,
neural networks, motor behavior and computational approaches, as well as
clinical applications for spinal cord injuries.

Conference Chairs

Ole Kiehn, M.D., Ph.D. Hans Hultborn, Ph.D.
University of Copenhagen, Denmark University of Copenhagen,
Denmark

Norio Kudo, M.D., Ph.D. Larry M. Jordan, Ph.D.
University of Tsukuba, Japan University of Manitoba, Canada

Ronald M. Harris-Warrick, Ph.D.
Cornell University, Ithaca, New York

Invited Participants:

Yuri I. Arshavsky, Ph.D.
Institute of Problems of Information Transmission Moscow, Russia

Hughes Barbeau, Ph.D.
McGill University Montreal, Canada

Deborah J. Baro, Ph.D.
Cornell University, Ithaca, New York

Robert E. Burke, M.D.
National Institutes of Health
Bethesda, Maryland

Jean-René Cazalets, Ph.D.
CNRS, Marseille, France

Milan R. Dimitrijevic, M.D., D.Sc.
Baylor College of Medicine
Houston, Texas

Joseph R. Fetcho, Ph.D.
State University of New York @Stony Brook

Barry Ganetzky, Ph.D.
University of Wisconsin, Madison

Sten Grillner, Ph.D.
Karolinska Institute, Stockholm, Sweden

Elzbieta Jankowska, Ph.D.
Göteborg University, Sweden

Paul S. Katz, Ph.D.
Georgia State University, Atlanta

Anders Lansner, Ph.D.
Royal Institute of Technology
Stockholm, Sweden

Eve Marder, Ph.D.
Brandeis University
Waltham, Massachusetts

Steven L. McIntire, Ph.D.
University of California, San Francisco

David A. McCrea, Ph.D.
University of Manitoba, Winnipeg, Canada

Michael O'Donovan, M.B.ChB., Ph.D.
National Institute of Neurological Disorders
and Stroke - NIH, Bethesda, Maryalnd

Keir G. Pearson, D.Phil.
University of Alberta, Edmonton, Canada

Alain M. Privat, M.D., Ph.D.
INSERM U. 336, Montpellier, France

Alan Roberts, Ph.D.
University of Bristol, United Kingdom

Serge Rossignol, M.D., Ph.D.
University of Montreal, Canada

Brian J. Schmidt, M.D.
University of Manitoba, Winnipeg, Canada

Allen I. Selverston, Ph.D.
University of California, San Diego
La Jolla, California

Karen A. Sigvardt, Ph.D.
University of California, Davis

Keith Sillar, Ph.D.
University of St. Andrews, Scotland

Paul S.G. Stein, Ph.D.
Washington University, St. Louis, Missouri

Preliminary Program

Friday, March 20

Registration and Welcome Reception

Saturday, March 21

Welcome Remarks and Introduction
Larry M. Jordan, Ph.D.

Presentation of the Best Understood Simple Motor Systems
Chair: Larry M. Jordan. Ph.D.

The Neuronal Network Underlying Locomotion in the Lamprey
Sten Grillner, Ph.D.
Central Circuits Controlling Locomotion in Young Frog Tadpoles
Alan Roberts, Ph.D.
Basic Principles for Generating Motor Output in the
Stomatogastric Ganglion Allen I. Selverston,
Ph.D.
Analysis of the Central Pattern Generator for Swimming in the
Mollusk Clione Yuri I. Arshavsky, Ph.D.
General Discussion

Principles for Spinal Locomotor Generation in Higher Vertebrates
Chair: Elzbieta Jankowska, Ph.D.

How Do We Approach Locomotor Networks in the Mammalian
Spinal Cord? Hans Hultborn, Ph.D.
Initiation of Mammalian Spinal Locomotor Systems Larry M. Jordan,
Ph.D.
Localization of Rhythm and Pattern-Generating Areas
in Mammals Ole Kiehn, M.D., Ph.D.
Mechanisms of Spontaneous Rhythmic Activity in the
Developing Spinal Cord Michael O'Donovan, M.B.Ch.B., Ph.D.
Reconstruction of Spinal Motor Pattern Generators in
the Turtle Paul S.G. Stein, Ph.D.
General Discussion

Poster Session

Chairs: Keith T. Sillar, Ph.D.
Eve Marder, Ph.D.

Sunday, March 22

Neurotransmitter Control of Pattern Generating Networks
Chair: Robert E. Burke, M.D.

General Principles for Neuromodulation of Small Motor Networks
Ronald M. Harris-Warrick, Ph.D.
GABA-ergic Control of Spinal Locomotor Network in the
Neonatal Rat Jean-René Cazalets, Ph.D.
Neuromodulation Intrinsic to the Central Pattern Generator
for Escape Swimming in Tritonia Paul S. Katz, Ph.D.
NMDA Receptor-Mediated Oscillatory Properties and Their
Potential Role in Rhythm Generation in the Mammalian
Spinal Cord Brian J. Schmidt, M.D.
General Discussion

Relation Between Afferents and Central Pattern Generators
Chair: Paul S.G. Stein, Ph.D.

Phenomenology and Functional Significance of Reflex
Reversal in the Walking Systems of Different SpeciesKeir G. Pearson,
D.Phil.
Neuronal Basis of Afferent-Evoked Enhancement of
Locomotor Activity David A. McCrea, Ph.D.
General Discussion

Modeling Approaches to Understanding Motor CPGs
Chair: Sten Grillner, Ph.D.

Modulation and Modeling of the Temporal Dynamics of
Network Function Eve Marder, Ph.D.
Modeling of the Spinal Neuronal Circuitry Underlying
Locomotion in a Lower Vertebrate Anders Lansner,
Ph.D.
Analysis and Modeling of the Locomotor CPG as a Network
of Coupled Oscillator Karen A. Sigvardt, Ph.D.
General Discussion

Molecular Determinants of Pattern Generator Components
Chair: Ronald M. Harris-Warrick, Ph.D.

Locomotion in C.elegans and Genes Necessary for GABA
Neuron Function Steven L. McIntire,
Ph.D.
The Molecular Basis for Heterogeneity of Ionic Conductances
in Single Cells in the Stomatogastric Ganglion Deborah J. Baro, Ph.D.
Molecular Analysis of Locomotor Mutants in DrosophilaBarry Ganetzky,
Ph.D.
General Discussion

Poster Session

Chairs: Karen Sigvardt, Ph.D.
Serge Rossignol, M.D., Ph.D.

Monday, March 23

Ontogeny and Phylogeny of Rhythmic Motor Activity
Chair: Michael O'Donovan, M.D., Ph.D.

Reorganization of Locomotor Activity During Development
in the Prenatal Rat Norio Kudo, M.D., Ph.D.
Reconfiguration of a Spinal Network for Locomotion by
Biogenic Amines Keith Sillar, Ph.D.
Imaging Ablations and Behavior: The Role of Neuronal
Populations in Movements of Zebrafish Joseph R. Fetcho, Ph.D.
General Discussion

Clinical Aspects of Locomotion and Rehabilitation
Chair: Hans Hultborn, Ph.D.

Pharmacological Activation and Modulation of Spinal CPG
in Chronic Spinal Cats Serge Rossignol, M.D.,
Ph.D.
Evidence for a Spinal CPG in Humans Milan R. Dimitrijevic, M.D.,
D.Sc.
Locomotor Adaptation in Spinal Cord Injured SubjectsHughes Barbeau,
Ph.D.
Recovery of Locomotion Following Transplantation of
Monoaminergic Neurons in the Spinal Cord of
Paraplegic Rats Alain M. Privat, M.D.,
Ph.D.
General Discussion

What Can We Learn From the Simple Motor Systems
When Approaching the More Complex Systems for
Locomotor Generation?
Chairs: Ronald M. Harris-Warrick, Ph.D. and Ole Kiehn, M.D., Ph.D.
Panel Participants: Allen I. Selverston, Ph.D., Sten Grillner, Ph.D.,
Keir G. Pearson, D.Phil., Robert E. Burke, M.D., Yuri I. Arshavsky,
Ph.D., Serge Rossignol, M.D., Ph.D., Elzbieta Jankowska, Ph.D. and Larry
M. Jordan, Ph.D.

Closing Remarks Larry M. Jordan, Ph.D.

Monday Evening, March 23

Conference Dinner
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CONFERENCE SPECIFICS

ACCME Credit
The New York Academy of Sciences is accredited by the Accreditation
Council for Continuing Medical Education to sponsor continuing medical
education for physicians. The New York Academy of Sciences designates
this continuing medical education activity for credit hours in Category
1 of the Physician's Recognition Award of the American Medical
Association; the number of credit hours will appear in the final
program.

Conference Location
The Caspary Auditorium at The Rockefeller University, 1230 York Avenue
(at 66th Street), New York City, will be the site of this conference.
The Rockefeller University and the Barbizon New York Hotel (see below)
are located in the upper eastside of Manhattan.

Accommodation Information
Hotel accommodations have been arranged with the Barbizon New York
Hotel, 140 East 63rd Street (at Lexington Avenue), New York, NY 10021,
at discounted rates of $145 single occupancy and $155 double occupancy
for a standard room and $175 single occupancy and $185 double occupancy
for a superior room. Standard rooms are limited and are available on a
first come first served basis. Rates are subject to a 13.25% tax plus a
$2.00 occupancy tax per room per night.

To make your reservation, contact the hotel directly by fax at
212-223-3287, or by calling 212-838-5700 or toll free within the USA at
1-800-223-1020. Reservation deadline: February 13, 1998. Reservations
received after February 13 will be subject to space and rate
availability. Indicate that you are attending a New York Academy of
Sciences meeting. Cancellations received within 48 hours of arrival are
subject to a penalty charge of one night's room and tax, per canceled
room. Check-in: 3:00 P.M. Check-out: 12:00 Noon.

Ground Transportation
Three airports service the New York City area: LaGuardia Airport
(domestic travel), John F. Kennedy (JFK) International Airport and
Newark International Airport (in New Jersey). Travel distance to upper
Manhattan is approximately 30 minutes from LaGuardia, 45 minutes from
JFK and 60 minutes from Newark airports. The Gray Line Air Shuttle
operates service from all three airports. Arrangements can be made at
the Ground Transportation Desk or the courtesy phone board in the
baggage claim area.

Air Travel Discounts
Special discounts for travel to Academy conferences are available for
all attendees and accompanying persons. For complete information on
applicable airlines and fares, contact the Academy's travel company
representative:

Travelquest
160 East 56th Street
New York, NY 10022
Tel: 212.223.0040 Fax: 212.421.0553
Attn: Ms. R. Chelouche

Poster Sessions
Contributed poster sessions will form an integral part of the conference
program. Deadline for submission of poster abstracts is January 16,
1998. The entire abstract, including title, author(s), and
affiliations, must be typed single-spaced and contained within a
rectangle that measures 5" x 4 3/8" or 12.5 cm x 11 cm (w x l); an
abstract form is not necessary. A separate cover letter should
accompany the abstract, indicating the conference name and the complete
mailing address (include e-mail address) and telephone/fax numbers of
the presenting author.

Send original abstracts to Renee Wilkerson, Meetings Coordinator, at the
New York Academy of Sciences.

Registration Fees Include:
Admittance to Scientific Sessions
Admittance to Poster Sessions
Registration Materials
Welcome Reception
Conference Dinner
Refreshments During Intermissions
Proceedings Published as a volume of the Annals of the New York
Academyof Sciences (not included in the daily registration rate)


Registration Fees:
Conference registration fees are waived only for invited speakers and
sessions chairs. Co-authors and poster presenters pay a registration
fee.

Before Feb. 13 After Feb. 13
1 NYAS Member $420 $470
2 Nonmember $495 $545
3 Resident/Fellow/Student* $280 $300
4 Daily (indicate date(s) on form) $190
$190
*Department Chair/Supervisor must sign registration form.
You are not officially registered until fees are received. You will be
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Refunds
Written requests for refunds postmarked by February 13 will be issued
minus an administrative fee of $50. Absolutely no refunds will be
honored after that date.

Send all correspondence to:
Science and Technology Meetings Department, New York Academy of
Sciences,2 East 63rd Street, New York, NY 10021.
Tel: 212.838.0230 ext. 324 Fax: 212.838.5640 E-mail:
conference@nyas.org
Visit the Academy at: http://www.nyas.org

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