We are currently looking for a quantitatively oriented young neuroscientist to
help develop a computational model of anesthetic action. The mechanism of
general anesthesia is currently unknown. It is now clear that anesthetics act
at multiple sites and that these may vary with the choice of anesthetic agent.
These sites affect both the electrical properties of cellular membranes and
the ability of neurons to signal other neurons. It is anticipated that such a
model will illuminate the contribution of each of these effects to the
anesthetic state, as well as the nature of the general anesthetic state.
The training period is two years, and the opportunity to perform the
necessary experiments to test and extend the model exists.
M.D.'s and/or Ph.D.'s are eligible.
For further information, please contact:
Allan Gottschalk, M.D., Ph.D.
Department of Anesthesia
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, Pennsylvania 19104
Phone: 215-662-3729
FAX: 215-662-7106
E-mail: ag@network3.entropy.upenn.edu$ Xwp