Symposium
Synaptic plasticity ou plasticities?
7e Colloque de la Société des Neurosciences
May 18th, 2005, 10.30 to 12.30 a.m., Lille, France
Organizers:
- Alain ARTOLA (Antwerpen, Belgium)
- Dominique DEBANNE (Marseille, France)
One of the remarkable properties of central nervous system is plasticity. And it is widely held that selective use-dependent changes in neuronal processing represent the physical substrate for information storage in the brain. Since the discoveries of long-term potentiation (LTP; Bliss and Lomo, J. Physiol. (Lond.) 232, 331, 1973) and long-term depression (LTD; Ito, Sakurai and Tongreach, J. Physiol. (Lond.) 324, 113, 1982), most attention have been focused on the mechanisms that translate a brief change in electrical activity patterns into a modification in synaptic efficacy. However, whereas LTP and LTD are likely central to memory storage, there are also reasons to believe that they are not the whole story. A rich variety of use-dependent plasticities have actually been described in the brain. Thus, synaptic activity can induce persistent changes in the intrinsic excitability of neurons. It can even elicit neuronal responses manifest only as shifts in the susceptibility to synaptic plasticity. Some of these plasticities will be presented in this symposium.
Speakers (alphabetical order)
Alain Artola
'Beyond LTD and LTP: the metaplasticity'
Abstract & Publications
Figures
Thierry Bal, Damien Debay, Jakob Wolfart, Mathilde Badoual, Zuzanna Piwkowska, Alain
Destexhe, Gwendal Le Masson
'Control of intrinsic and integrative properties by background synaptic bombardment in biological
and hybrid networks'
Abstract, Publications & Figures
Dominique Debanne, Gal Daoudal, Emilie Campanac
'Bidirectional plasticity of synaptic integration in CA1 pyramidal neurons: learning rules and
mechanisms'
Abstract
Publications
Figure1
Figure2
Didier Le Ray
'Metaplasticity: role in the selection of convergent synaptic inputs'
Abstract, Publications & Figures
Olivier J. Manzoni
'Retrograde synaptic plasticity and metaplasticity induced by addictive drugs in the nucleus
accumbens and the prefrontal cortex'
Abstract
Publications
Figures
Jean Christophe Poncer
'LTP and the plasticity of release dynamics'
Abstract & Publications
Figure1
Figure2
