[Comp-neuro] Paper on "orientation adaptation induced plasticity"

[Ketan Bajaj]

Dear All,
I'd like to bring to your attention our paper on
orientation adaptation induced plasticity in adult
primary visual cortex.

Title: 
Adaptation-induced suppression and facilitation:
Effect of intra- and extracellular ionic disturbances,
Neurocomputing, 70, 1695-1701, 2007.

Keywords: 
Adaptation, Calcium, Extracellular, Mitochondria,
Orientation plasticity

URLs:
http://portal.acm.org/citation.cfm?id=1241225
http://linkinghub.elsevier.com/retrieve/pii/S0925231206003651

Abstract:
Adaptation to drifting-oriented gratings has been
shown to cause orientation plasticity. To study
adaptation induced responses we have developed a V1
population model having isotropic intracortical
synaptic connections, incorporating sub-cellular and
intrinsic membrane mechanisms. The model captures the
finer details of recently reported experimental
results on orientation plasticity and shows that
pinwheel centers are foci of orientation plasticity.
The model captures the tilt aftereffect and further
explains how orthogonal adaptation can lead to
sharpening of orientation tuning curves. We report
here for the first time that adaptation not only
causes response suppression but can simultaneously
increase the excitability of the local neural tissue
due to accumulated extracellular ionic disturbances.
The increased excitability can lead to response
facilitation for cells having the least intracellular
ionic disturbances. 

Regards,
Ketan Bajaj
http://www.geocities.com/bajajketan/index.html


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